Validation of anti-malarial leads from natural products and traditional medicine for treatment of malaria

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningfagfællebedømt

In the first part of this chapter antimalarial drugs derived from natural products are mentioned. The mentioned drugs are quinine and other quinolone derivatives, derivatives of artemisinin, tetracyclines, macrolides, lincosamide and malarone derived from naturally occurring naphthoquinones. The recently registered drugs bulaquine and tafenoquine are also included. The mechanisms of action, clinical effects and development of resistance are discussed. In the second part are results from clinical trials of traditional medicines marketed as antimalarial drugs discussed. Clinical trials on drug derived from Argemone mexicana, Artemisia annua, Vernonia amygdalina and Cochlospermum species are described.
OriginalsprogEngelsk
TitelIn Evidence-Based validation of herbal medicine
RedaktørerP. K. Mukherjee
UdgivelsesstedAmsterdam
ForlagElsevier
Publikationsdato2022
Udgave2
Sider389-407
Kapitel15
ISBN (Elektronisk)978-0-323-85542-6
DOI
StatusUdgivet - 2022

ID: 315262122